The ASPiRE team from the University of North Carolina argues that retail policy changes in that state would bolster attempts to reduce youth tobacco use and eliminate tobacco-related disparities. The commentary, published in the North Carolina Medical Journal, describes the evidence for point-of-sale policies including Tobacco 21 laws, restrictions on advertising and promotions, flavored tobacco restrictions, tobacco retailer licensing, and the repeal of state laws prohibiting local restrictions. ASPiRE authors on the project were Sarah Halvorson-Fried, Alexandria Reimold, Sarah Mills, and Kurt Ribisl. Read the commentary.